About this product
ARA Vial is supplied at 16mg/3ml. [Per-product description to be added.]
What It Does
Six Reasons Clinicians Recommend ARA-290 (Cibinetide)
A synthetic 11-amino acid peptide engineered from the tissue-protective domain of Erythropoietin (EPO) — isolated specifically for its nerve repair and anti-inflammatory properties while eliminating EPO's red blood cell-stimulating effects. ARA-290 activates the Innate Repair Receptor (IRR) to produce targeted neuroprotection, pain reduction, and tissue repair without the cardiovascular risks of EPO itself.
EPO (Erythropoietin)
Stimulates red blood cell production AND activates tissue-protective receptors. The RBC-stimulating effect carries cardiovascular risks — thromboembolic events, hypertension — that limit its use to severe anemia. Its tissue-protective effects are overshadowed by these risks.
ARA-290 (Cibinetide)
Engineered from EPO's tissue-protective domain only — activating the Innate Repair Receptor (IRR) without stimulating red blood cell production. All the neuroprotective and anti-inflammatory benefits of EPO's tissue-protective signaling, without the hematological and cardiovascular risks.
Nerve Repair & Peripheral Neuropathy Relief
ARA-290's most established clinical application is in painful peripheral neuropathy — particularly diabetic neuropathy and neuropathy associated with sarcoidosis. Phase 2 clinical trials demonstrated significant reductions in neuropathic pain scores, improved nerve fiber density in skin biopsies, and restored small fiber nerve function in treated patients. By activating the Innate Repair Receptor on Schwann cells and neurons, ARA-290 supports the survival, repair, and remyelination of damaged peripheral nerve fibers that conventional pain medications do not address.
Potent Anti-Inflammatory Action
ARA-290 activates the Innate Repair Receptor (IRR) — a heteroreceptor complex that shifts tissue from an inflammatory state toward a repair and regeneration state. IRR activation suppresses pro-inflammatory cytokine production including TNF-α, IL-1β, and IL-6, while simultaneously upregulating anti-inflammatory and tissue-protective signaling pathways. This mechanism is particularly relevant in autoimmune and inflammatory conditions where sustained cytokine activity drives ongoing tissue damage despite conventional treatment.
Sarcoidosis & Autoimmune Support
ARA-290 has been specifically studied in sarcoidosis — a chronic inflammatory disease affecting multiple organ systems — where it demonstrated improvements in neuropathic pain, fatigue, and quality of life in Phase 2 trials. The IRR activation mechanism directly addresses the inflammatory cytokine environment that drives sarcoidosis pathology. For patients with systemic inflammatory conditions inadequately controlled by conventional immunosuppressants, ARA-290 offers a novel anti-inflammatory mechanism targeting the tissue-protective receptor system that EPO naturally engages.
Neuroprotection & CNS Support
The Innate Repair Receptor is expressed throughout the central nervous system, where ARA-290's activation supports neuronal survival, reduces neuroinflammation, and promotes the repair of CNS tissue under inflammatory and ischemic stress. EPO's neuroprotective effects in stroke and traumatic brain injury models are well-documented — ARA-290 isolates this tissue-protective CNS activity without EPO's hematological risks, making it a candidate for neurological conditions involving chronic neuroinflammation and neuronal stress.
Metabolic & Insulin Sensitivity Support
Emerging research suggests ARA-290 improves insulin sensitivity and metabolic function through IRR activation in pancreatic beta cells and metabolic tissue — supporting beta cell survival, reducing the inflammatory environment that drives insulin resistance, and improving glucose metabolism parameters. In the sarcoidosis trials, patients showed improvements in metabolic markers alongside their neuropathic pain reductions — suggesting systemic metabolic benefits from IRR activation that extend beyond the nervous system.
Tissue Protection & Organ Repair
EPO's tissue-protective domain — which ARA-290 isolates — was identified through research showing EPO protects multiple organ systems from ischemic and inflammatory damage independent of its hematopoietic effects. ARA-290 inherits this broad tissue-protective activity, with research documenting protective effects in cardiac, renal, retinal, and neural tissue under stress conditions. This systemic organ-protective potential positions ARA-290 as a candidate for conditions involving multi-system inflammatory tissue damage beyond its primary neuropathy indication.
Engineered From One of Medicine's Most Studied Molecules
Erythropoietin (EPO) is one of the most extensively characterized proteins in medicine — decades of research on its tissue-protective effects identified a specific domain responsible for neuroprotection and repair that is entirely separate from its hematopoietic activity. ARA-290 was engineered by isolating and synthesizing this protective domain — making it a precision therapeutic tool that delivers EPO's protective signaling where it is needed without the systemic risks that have limited EPO's use to severe anemia. Phase 2 human clinical trials in diabetic neuropathy and sarcoidosis validate the mechanism in human populations.
* These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Available with a valid physician consultation only.
Formulated by Dr. Sasson Moulavi
Every Lavi MD peptide is developed under the direction of Dr. Sasson Moulavi, the physician behind the brand. Formulations are built to clinical specification, not sourced from anonymous suppliers.
Dr. Moulavi earned his Doctor of Medicine from the University of Toronto and completed postgraduate training at McGill University in Montreal. He holds Board Certification in Anti-Aging Medicine and Bariatric Medicine, and is a member of the American Academy of Anti-Aging Medicine and the American Society of Bariatric Physicians. With over three decades of clinical experience in bariatric, family, and anti-aging medicine, he serves as Medical Director and prescribing physician for Lavi MD, overseeing formulation standards and clinical protocols.
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Why Lavi MD
Not All Peptide Brands Are Equal
Most peptide suppliers prioritize volume over patients. We were built differently — by a physician, for patients.
Brands / Suppliers
Medical Director on Staff
Sasson Moulavi, MD
Dispensing Physician · Chayim Therapeutics, LLC
West Palm Beach, FL
"Every product we offer is something I would prescribe to my own patients. Our formulations are designed for clinical outcomes — not marketing claims."
How We Operate
Built by a Physician, Not a Marketing Team
Lavi MD was founded under physician supervision. Every formulation, every dose, every protocol is reviewed by Dr. Moulavi before it reaches a patient — not outsourced to a contract manufacturer with no clinical input.
We Limit Shipping Days to Protect Your Product
We only ship Monday and Tuesday. That's a deliberate decision — it ensures your order arrives before the weekend and never sits in a carrier facility over two days without refrigeration. Most brands don't think that far ahead.
We Treat You Like a Patient, Not an Order Number
Our team includes clinical staff who understand what you're taking and why. If something goes wrong with your order — a warm shipment, a missing component, a question about your protocol — we fix it. No automated runaround.
Proud Members of the
American Peptide Association
The American Peptide Association is the leading industry body advancing the science, safety, and standards of peptide research. Our membership reflects our unwavering commitment to purity, transparency, and responsible sourcing — giving you full confidence in every product you purchase.
